Conserved modules drive evolution of signaling network
Last modified Thu, 21 Aug, 2014 at 12:11
Methylation of MAP3K2 stimulates tumorigenesis
Wednesday, August 20, 2014
Last modified Thu, 21 Aug, 2014 at 9:31
Biology Professor Or Gozani and collaborators showed that SMYD3, a methyltransferase enzyme, methylates MAP3K2, a key component in MAP kinase signaling. SMYD3 is overexpressed in several human tumors and compromising SMYD3 activity resulted in inhibition of tumors that develop in response to activated RAS oncogene, suggesting that SMYD3 might be a target for cancer therapy
Last modified Wed, 20 Aug, 2014 at 22:54
Our department includes both undergraduate and graduate programs, with over 110 graduate students and 90 postdoctoral fellows from all over the world. Research areas include Molecular Biology, Cell Biology, Developmental Biology & Genetics; Plant Biology; Population and Evolutionary Biology and Ecology; and Marine Biology.