Stephen Buratowski - “Visualizing RNA pol II transcription dynamics in real time”

“Visualizing RNA pol II transcription dynamics in real time”

Stephen Buratowski

Steve Buratowski received his undergraduate degree summa cum laude from Princeton University in 1984.  He did his Ph.D. thesis work with Dr. Phillip A. Sharp at MIT (1990) and then spent four years as an independent Whitehead Institute Fellow. In 1994 he joined the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School, where he was tenured in 2001.  He has been honored as a Pew Scholar, a Stohlman Scholar of the Leukemia and Lymphoma Society, and an American Academy of Microbiology Fellow. Dr. Buratowski's research has provided fundamental insights into the mechanisms of eukaryotic gene expression by RNA polymerase II and its associated factors. In particular, he is recognized for discovering how transcription initiation and elongation are coupled to RNA processing and chromatin modifications via a cycle of distinct polymerase phosphorylations (often called the "CTD code"). Recent studies in the Buratowski lab focus on transcription dynamics using genomic, proteomic, and single molecule microscopy techniques.

Host: Jan Skotheim