Sue Biggins - “Detecting and Correcting Errors in Mitosis”

Dr. Sue Biggins earned a doctoral degree in molecular and cellular biology from Princeton University. She performed her postdoctoral work in Dr. Andrew Murray's lab at UCSF and then joined the faculty of Fred Hutch in 2000.  Her lab studies the mechanisms that ensure accurate chromosome segregation and regulation of the cell cycle. Her lab achieved the first isolation of kinetochores and has been applying structural, biophysical and biochemical techniques to elucidate the mechanisms of kinetochore-microtubule interactions and spindle checkpoint regulation. Her lab also works on the mechanisms that ensure chromatin composition and centromere identity